FANCC (NM 000136) Humaan Recombinant eiwit

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2) . The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq, Jul 2008]

Purified recombinant protein of Human Fanconi anemia, complementation group C (FANCC), Met1-Ala284, with N-terminal His tag, expressed in E. coli, 50ug

FA3; FAC; FACC

2176

Q00597, A0A024R9N2

NM_000136

9q22.32

E. coli

N-His

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0.

Druggable Genome

32.5 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

FANCC

Human

NP_000127

https://www.ncbi.nlm.nih.gov/gene/2176

https://www.uniprot.org/uniprot/Q00597

https://www.ncbi.nlm.nih.gov/nuccore/NM_000136

https://www.ncbi.nlm.nih.gov/nuccore/NP_000127