FAP targeting peptide voor FXX489

FAP targeting peptide for FXX489 is the polypeptide part of Unlabeled FXX489. Unlabeled FXX489 is a fibroblast activation protein (FAP) -targeting ligand[1].

3076328-74-7

12352209

FAP; Radionuclide-Drug Conjugates (RDCs)

Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

Cancer-programmed cell death

Cancer

99.49

DMSO : 100 mg/mL (ultrasonic)

NCC1=CC=C(C[C@H](NC([C@H](CC2=CC=CC=C2)N(C)C(CNC(CNC([C@H]3CCCN3C([C@H](CC(O)=O)NC([C@H](CCCCNC(N4CCN(CC(O)=O)CC4)=O)NC(CN5)=O)=O)=O)=O)=O)=O)=O)C(N[C@@H](CCCCCC)C(N[C@@H](CC6=CNC7=C6C=CC=C7)C5=O)=O)=O)C=C1

C67H91N15O15

1346.53

[1]Ravit Geva, et al. Abstract CT112: Phase I open-label, multi-center study to evaluate the safety, tolerability, dosimetry, and preliminary activity of FXX489 ([177Lu]Lu-NNS309) in patients with pancreatic, lung, breast and colorectal cancers. Cancer Res (2025) 85 (8_Supplement_2) : CT112.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P10945/FAP-targeting-peptide-for-FXX489-SDS-MedChemExpress.pdf

Peptides

No Development Reported

RDC Peptide