Fas Ligand / FASLG / CD95L eiwit (Zijn label)
Gecertificeerd

Fas Ligand / FASLG / CD95L eiwit (Zijn label)

Catalog #: 600-110-L1000
Maat: 1000 µg
Droogijs Vereist

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Technische Specificaties

Description

Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

Synonyms

ALPS1B Protein; APT1LG1 Protein; APTL Protein; CD178 Protein; CD95-L Protein; CD95L Protein; FASL Protein; TNFSF6 Protein; TNLG1A Protein

Accession Number

NP_000630.1

Reactivity

Human

Cross Reactivity

Human

Label

His-Tag

Assay Protocol

See Datasheet send with the product

Endotoxin

Please contact us for more information.

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Immobilized Human Fas/CD95 hFc at 2 μg/mL (100 μL/well) can bind Human Fas Ligand His , the EC50 of Human Fas Ligand His is 40-200 ng/mL.

Length

168

Form

Lyophilized or frozen liquid

Buffer

PBS, pH 7.4

Reconstitution

See Datasheet

Molecular Weight

26 kDa

Storage Conditions

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Host or Source

Yeast

Beschrijving

Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand i

Specificaties

ProductnaamFas Ligand / FASLG / CD95L eiwit (Zijn label)
Categorie
Beschikbare grootte1000 µg
Catalogusnummer600-110-L1000