FasLG-antilichaam

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE) . Alternatively spliced transcript variants have been described.

356

P48023

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FasLG (NP_000630.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity, Stem Cell

Affinity purification

Mouse heart

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 33kDa

IgG

WB: 1:500 - 1:2000

FasLG

Fas ligand (TNF superfamily, member 6)

Homo sapiens

FASLG, ALPS1B, Apoptosis antigen ligand, APTL, CD95L, CD95 ligand, CD178 antigen, CD95-L, Fas antigen ligand, Fas ligand, FASL, TNFSF6, APT1LG1, CD178

WB

Liquid