FB23-2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
FB23-2 is an inhibitor (IC50 = 2.6 µM) of the mRNA m6A demethylase fat-mass- and obesity-associated protein (FTO) .1 Displays significant anti-proliferative activity in NB4 (IC50 = 0.8 µM) and MONOMAC6 (IC50 = 1.5 µM) cells. Selective against the RNA demethylase ALKB5. FB23-2 induced myeloid differentiation and apoptosis in acute myeloid leukemia cells. FB23-2 suppressed the proliferation and migration of hepatocellular carcinoma cells via suppressing the expression of the kinase ERBB3 and human tubulin beta class Iva (TUBB4A) .2
Unconjugated
Off-white solid
-20°C
Beschrijving
FB23-2 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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