FBL Antilichaam

This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.

2091

P22087

Human, Mouse, Rat, Monkey

Recombinant fusion protein containing a sequence corresponding to amino acids 100-321 of human FBL (NP_001427.2) .

Unconjugated

Primary Antibodies

Other

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 37kDa

IgG

FBL

A375

U-2OS

COS-1

COS-7

PC-12

Fibrillarin

Homo sapiens

FBL, FIB, FLRN, RNU3IP1

WB, IHC, IF, IP

Liquid