FBXL16 Antilichaam

FBXL16 Antibody: FBXL16 (F-box and leucine-rich repeat protein 16), a member of the F-box protein family, is a probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein) -type E3 ubiquitin ligase complex. It is characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F-box, and they interact with ubiquitination targets through other protein interaction domains. FBXL16 is a novel E2F1-regulated gene in crucial cell cycle regulation pathways.

146330

Q8N461

NP_699181

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

FBXL16 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1306 - Human Spleen Tissue Lysate

1 mg/mL

FBXL16 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

FBXL16 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

FBXL16 antibody is predicted to not cross-react with other F-box protein family members.

FBXL16

Cat. No. 10-901 - Human Spleen Tissue Slide

F-box and leucine-rich repeat protein 16

Homo sapiens

Martin J, Han C, Gordon LA, et al. The sequence and analysis of duplication-rich human chromosome 16. Nature2004; 432:988-94.

Jin J, Cardozo T, Lovering RC, et al. Systematic analysis and nomenclature of mammalian F-box proteins. Genes Dev.2004; 18:2573-80.

Sato K, Kusama Y, Tategu M, et al. FBXL16 is a novel E2F1-regulated gene commonly upregulated in p16INK4A- and p14ARF-silenced HeLa cells. Int. J. Oncol.2010; 36:479-90.

FBXL16 Antibody: Fbl16, C16orf22, c380A1.1, FBL16, F-box and leucine-rich repeat protein 16

ELISA, WB, IHC-P, IF

289666746

Liquid