FBXL5 Antilichaam - middengebied: Biotine (ARP43104_T100-Biotine)

F-box and leucine-rich repeat protein 5

FBL4, FBL5, FLR1

26234

Q9UKA1

NP_036293

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human FBXL5

FBXL5 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL5 belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternative splicing of this gene generates 2 transcript variants.

NABP2; CUL1; SNAI1; SKP1; FBXL5; HERC2; UBC; IREB2; ACO1; RBX1; MUS81; MMS19; FAM96B; ORC4; EP300; SMURF1; BTG1; COPS5; PLK1; CSNK2B; DCTN1

Biotin

Polyclonal Antibody

IHC, WB

0.5 mg/ml

Cow: 86%; Dog: 93%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 86%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

76kDa

Ilyin, G.P., (2000) Genomics 67 (1), 40-47

Wet Ice

691

FBXL5

FBXL5

Rabbit

F-box/LRR-repeat protein 5

NM_012161

VHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES