FBXO21 Polyklonale Antilichaam, APC-Cy7 Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.
F box only protein 21; F box protein 21; F-box only protein 21; FBX21; FBX21_HUMAN; Fbxo21; FLJ90233; KIAA0875; MGC26682.
23014
• Rabbit
Human, Rat
65-170/628
FBXO21
• Polyclonal
• IgG
APC-Cy7
KLH conjugated synthetic peptide derived from human FBXO21
WB, IF (IHC-P)
Purified by Protein A.
650nm/780nm
1µg/µl
WB (1:300-5000), IF (IHC-P) (1:50-200)
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
23014
Mouse, Dog, Cow, Sheep, Pig, Rabbit
Beschrijving
FBXO21 Polyklonale Antilichaam, APC-Cy7 Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
Specificaties
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HyperLadder 1kb
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