FBXO31 Antilichaam - middengebied HRP (ARP53775 P050-HRP)

F-box protein 31

FBX14, Fbx31, MRT45, FBXO14, pp2386

79791

Q5XUX0

NP_079011

Human

The immunogen is a synthetic peptide directed towards the middle region of human FBXO31

FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.

CDT1; UBE2L6; UBE2D1; CCND1; CUL1; MAP2K6; PARD6A; SKP1; COPS5; RBX1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

40kDa

Wet Ice

367

FBXO31

FBXO31

Rabbit

F-box only protein 31

NM_024735

QGPRESQPSPAQPRAEAPSKGPDGTPGEDGGEPGDAVAAAEQPAQCGQGQ