FBXW11 Antilichaam - N-terminalgebied: FITC (ARP43379 P050-FITC)

F-box and WD repeat domain containing 11

Hos, BTRC2, FBW1B, Fbw11, BTRCP2, FBXW1B, NEDJED

23291

Q9UKB1

NP_387448

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human FBXW11

FBXW11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

ELMO2; NCKAP5L; USP37; CACHD1; ZNF395; TACC1; STK4; STK3; SKP1; REST; RELA; RAP1GAP; PFDN5; PFDN4; NRD1; NFKB2; NFKB1; NFE2L2; NEDD8; MAX; LRCH4; ILF3; FOXN2; HNRNPU; HIVEP2; HIVEP1; HCFC1; EZH2; DOCK1; DHX9; CTNNB1; CTNNA1; CLTC; CHD1; CDC34; CDC25B; CDC

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

FBXW11 is supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

61kDa

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Wet Ice

529

FBXW11

FBXW11

Rabbit

F-box/WD repeat-containing protein 11

NM_033644

EPDSVIEDKTIELMNTSVMEDQNEDESPKKNTLWQISNGTSSVIVSRKRP