Fc epsilon receptor I alfa antilichaam [FCER1]

The Mar-1 monoclonal antibody binds to the Fc epsilon Receptor I alpha subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily. FceR1a lacks signal-transducing ability and is expressed by mast and basophil cells.The Fc epsilon Receptor I alpha subunit is upregulated by IgE and forms a tetramer with a beta subunit and two gamma subunits, which have ITAM (immunoreceptor tyrosine-based activation motifs) . The complex formed by the four subunits has very important roles in the IgE-facilitated allergic reactions.

2205

P12319

Mouse

FceR1

Unconjugated

Primary Antibodies

Innate Immunity

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Armenian Hamster IgG

The Mar-1 monoclonal antibody binds to the Fc epsilon Receptor I alpha subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily.

FCER1A

Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide

Homo sapiens

FCE1A, FcER, FCER1A

Flow, Functional Assays, IHC, IP

Liquid