FCGRT & B2M eiwit (C-AVI & zijn, mens)

FCGRT & B2M

C-AVI & His

< 1.0 EU per μg protein as determined by the LAL method.

≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC. ≥ 90 % as determined by SEC-MALS (Routinely tested) .

1.Loaded Biotinylated Human FcRn recombinant protein (His & Avi Tag) (Cat. CT071-H27H-B) on SA Biosensor, can bind IgG1 Fc (IgG1) (Cat. 10702-HNAC) with an affinity constant of 0.073 μM as determined in a BLI assay (Sartorius Octet Red384) . 2.Loaded Biotinylated Human FcRn recombinant protein (His & Avi Tag) (Cat. CT071-H27H-B) on SA Biosensor, can bind IgG4 Fc (Cat. 13505-HNAH) with an affinity constant of 0.070 μM as determined in a BLI assay (Sartorius Octet Red384) . 3.Loaded Recombinant Human FCGRT & B2M Heterodimer Protein, His & AVI Tag, Biotinylated (Cat. No. CT071-H27H-B) on SA Biosensor, can bind Anti-PD1 Antibody, human IgG4 with an affinity constant of 11 nM as determined in BLI assay (Sartorius Octet RED384) (QC tested) . 4.Biotinylated Recombinant Human FCGRT & B2M Heterodimer Protein, AVI & His Tag (Cat. No. CT071-H27H-B) captured on NTA chip, can bind Herceptin with an affinity constant of 0.162 μM as determined in an SPR assay (Biacore T200) (Routinely tested) .

Met1-Ser297 & Met1-Met119

The recombinant heterodimer of human FCGRT/B2M comprises 399 (300+99) amino acids and has a calculated molecular mass of 45.3 (33.6+11.7) KDa. The molecular weight of this protein is around 46-56 kDa verified by SEC-MALS (Routinely tested) .

Human