FCHO2 Antilichaam

FCHO2 Antibody: FCHO2 (FCH domain only 2) is a ubiquitously expressed member of the FCFBS superfamily characterized by FES-CIP4 homology (FCH) domain, an FBH domain, and an SH3 domain. Both FCHO2 and the related protein FCHO1 are mediators of clathrin-mediated endocytosis, acting to sculpt the initial bud site and recruit the clathrin machinery for clathrin-coated vesicle formation. FCHO2 binds to Eps15, an important adaptor protein in clathrin-mediated endocytosis.

115548

Q0JRZ9

NP_620137

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

FCHO2 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1461 - Rat Heart Tissue Lysate

1 mg/mL

FCHO2 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

FCHO2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

FCHO2 antibody is predicted to not cross-react with other FCHO protein family members. At least the isoforms of FCHO2 are known to exist; this antibody will detect only the two longest isoforms.

FCHO2

Cat. No. 10-501 - Human Heart Tissue Slide

FCH domain only 2

Homo sapiens

Katoh M and Katoh M. Identification and characterization of human FCHO2 and mouse fcho2 genes in silico. Int. J. Mol. Med. 2004; 14:327-31

Henne WM, Boucrot E, Meinecke M, et al. FCHo proteins are nucleators of clathrin-mediated endocytosis. Science 2010; 328:1281-4.

Uezu A, Umeda K, Tsujita K, et al. Characterization of the EFC/F-BAR domain protein, FCHO2. Genes Cells 2011; 16:868-78.

FCHO2 Antibody: FCH domain only protein 2

ELISA, WB, IHC-P, IF

226371723

Liquid