FCRL4 Antilichaam

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.

83417

Q96PJ5

Q96PJ5

Human

This FCRL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-507 amino acids from the C-terminal region of human FCRL4.

Unconjugated

Primary Antibodies

Immunology

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

57 kDa

Rabbit Ig

FCRL4

Fc receptor-like protein 4

Homo sapiens

Davila, S., et al. Genes Immun. (2010) In press :

Weiss, G.E., et al. J. Immunol. 183 (3) :2176-2182 (2009)

Kazemi, T., et al. Cancer Immunol. Immunother. 58 (6) :989-996 (2009)

Falini, B., et al. Blood 102 (10) :3684-3692 (2003)

Fc receptor-like protein 4, FcR-like protein 4, FcRL4, Fc receptor homolog 4, FcRH4, IFGP family protein 2, hIFGP2, Immune receptor translocation-associated protein 1, CD307d, FCRL4, FCRH4, IFGP2, IRTA1

WB, Flow

74761029

Liquid