FDFT1 Antilichaam - N-terminalgebied: FITC (ARP48630_T100-FITC)

Farnesyl-diphosphate farnesyltransferase 1

SS, SQS, DGPT, ERG9, SQSD

2222

P37268

NP_004453

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human FDFT1

FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UBC; MDM2; FBXO6; EGFR; GLP1R; HDAC10; UBL4A; FN1; UBD; RUVBL2; TMEM43; FAM101A; SHPRH; ARL6IP1; ANXA5; SMNDC1; PSTPIP1; RUVBL1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

FDFT1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

48kDa

Do, R., (er) Hum. Mutat. (2008) In press

Wet Ice

417

FDFT1

FDFT1

Rabbit

Squalene synthase

NM_004462

HSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRM