FECH Polyklonale Antilichaam, PE-Cy7 Vervoeging

Ferrochelatase catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway, and is localised in the mitochondrion. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. Porphyrias are a group of inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway (also called porphyrin pathway) . They are broadly classified as hepatic porphyrias or erythropoietic porphyrias, based on the site of the overproduction and mainly accumulation of the porphyrins (or their chemical precursors) . They manifest with either skin problems, or neurological complications, or occasionally both.

EPP; FCE; Ferrochelatase protoporphyria; Ferrochelatase; Ferrochelatase mitochondrial; Heme synthetase; Protoheme ferro lyase; HEMH_HUMAN.

2235

Human, Mouse, Rat

81-180/423

FECH

PE-Cy7

KLH conjugated synthetic peptide derived from human EPB41

WB

Purified by Protein A.

488nm/780nm

1µg/µl

WB (WB=1:500-2000)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

2235