Fedratinib (TG101348)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
936091-26-8
SAR302503
C08814-5mg
JAK
Angiogenesis
CC1=CN=C (N=C1NC2=CC (=CC=C2) S (=O) (=O) NC (C) (C) C) NC3=CC=C (C=C3) OCCN4CCCC4
C27H36N6O3S
Fedratinib (SAR302503, TG101348) is a selective inhibitor of JAK2 with IC50 of 3 nM in cell-free assays, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Fedratinib also inhibits FMS-like tyrosine kinase 3 (FLT3) and RET (c-RET) with IC50 of 15 nM and 48 nM, respectively. Fedratinib has potential antineoplastic activity. Fedratinib inhibits proliferation and induces apoptosis. Phase 2.
2 years -80 in solvent
Beschrijving
Fedratinib (TG101348) Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
AffiniPure Goat Anti-Rabbit IgG H&L, HRP conjugated
GTR17765564-01
100 µL
Pribolab® Automatic Immunoaffinity Column Purification System
HWEQ-IM 5050
1 Unit
OneTaq Hot Start 2X Master Mix with GC Buffer
NEB M0485L
500 Reactions
HyperLadder 1kb
BIO-33053
100 Lanes
MicroMolar UDP assay kit - 100 assays
MUD100K
100 Assays
MEM Amino Acids Solution (50x) w/o: L-Glutamine
P08-30100
100 mL
White glass slide, frosted
1380-20
1440/CS
Anti-TNF-α (Adalimumab), humanized Antibody
A1048-100
100 µg