FEN1 Polyklonale Antilichaam, PE-vervoeging
Gecertificeerd

FEN1 Polyklonale Antilichaam, PE-vervoeging

Catalog #: bs-9876R-PE
Maat: 100 µL

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Technische Documentatie

Technische Specificaties

Background

Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.

Synonyms

DNase IV; FEN-1; FEN1; FEN1_HUMAN; Flap endonuclease 1; Flap structure specic endonuclease 1; Flap structure-specic endonuclease 1; hFEN-1; hFEN1; Maturation factor 1; MF1; Rad2.

Gene ID

2237

Host

• Rabbit

Cross Reactivity

Mouse

Immunogen

165-260/380

Target

FEN1

Clonality

• Polyclonal

Isotype

• IgG

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human FEN1

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2237

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit

Beschrijving

FEN1 Polyklonale Antilichaam, PE-vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamFEN1 Polyklonale Antilichaam, PE-vervoeging
Categorie
Beschikbare grootte100 µL
Catalogusnummerbs-9876R-PE