Fenicine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Phenicin (Phoenicine), a microbial metabolite, is an irreversible HMG-CoA reductase (HMGCR) inhibitor. Phenicin can be isolated from cultures of Penicillium phoeniceum and Penicillium rubrum. Phenicin specifically inhibits the conversion of HMG-CoA to mevalonate catalyzed by HMGCR, effectively inhibiting cholesterol synthesis[1].
128-68-7
Phoenicine
12352211
HMG-CoA Reductase (HMGCR)
Metabolic Enzyme/Protease
Metabolism-sugar/lipid metabolism
Others
O=C1C=C(C)C(C(O)=C1C(C(C=C2C)=O)=C(O)C2=O)=O
C14H10O6
274.23
[1]Hasumi K, et al. Irreversible inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by phenicin (phoenicine) . J Antibiot (Tokyo) . 1987 Feb;40 (2) :224-6.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N16439/
Natural Products
No Development Reported
Beschrijving
Phenicin (Phoenicine), a microbial metabolite, is an irreversible HMG-CoA reductase (HMGCR) inhibitor. Phenicin can be isolated from cultures of Penicillium pho
Specificaties
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