Ferrocine B

Ferrocin B is an iron-containing cyclic decapeptide antibiotic found in the bacterium Pseudomonas fluorescens YK-310, exhibiting strong antibacterial activity primarily against Gram-negative bacteria, with particularly potent inhibitory effects on Pseudomonas aeruginosa. In a mouse infection model, Ferrocin B shows a half effective dose (ED50) of 0.593 mg/kg against P. aeruginosa. Ferrocin B holds potential for research in the field of anti-infective therapies[1].

114562-40-2

12352211

Antibiotic; Bacterial

Anti-infection

Infection

O=C1OCC(C(NC2C(NCC(NC(C(C)C)C(NC(CO)C(NC3C(NC(CO)C(NCC(NC(CCCN4[O-][Fe+3]56(O=C(C)N(CCC2)[O-]5)(O=C(C)N(CCC3)[O-]6)O=C4C)C(NC1)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC(C/C=C/CCCCCC)=O

C51H82FeN13O20

1253.12

[1]Katayama N, et al. Ferrocins, new iron-containing peptide antibiotics produced by bacteria. Taxonomy, fermentation and biological activity. J Antibiot (Tokyo) . 1993 Jan;46 (1) :65-70.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N14354/

Natural Products

No Development Reported