FES Antilichaam - N-terminaal gebied: Biotine (ARP54608_P050-Biotine)

Feline sarcoma oncogene

FPS

2242

P07332

NP_001996

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human FES

FES is the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

MDFI; HSP90AA1; EGFR; UBC; TRIM28; POT1; TERF1; NEDD4; ZNF775; ZNF746; PDE4DIP; HSH2D; PLXNA1; DPYSL5; RASA3; BCAR1; DOK1; IRS2; JAK3; FES; PIK3R1; BCR; JAK2; JAK1; IL4R; IRS1; RASA1; CSF2RB; STAT3; PTGES3; PPID; HSPA4; FKBP5; FKBP4; PSMD13

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 88%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

93kDa

Naba, A., (2008) EMBO J. 27 (1), 38-50

Wet Ice

822

FES

FES

Rabbit

Tyrosine-protein kinase Fes/Fps

NM_002005

ARDSAQAKRKYQEASKDKDRDKAKDKYVRSLWKLFAHHNRYVLGVRAAQL