FFS-21
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of betaKlotho as a protein cofactor, signals through the FGFR 1c and 4 receptors and stimulates insulin independent glucose uptake by adipocytes. Recombinant human FGF-21 is a 19.5 kDa protein containing 182 amino acid residues.
FGF21
26291
Q9NSA1
NP_061986.1
NM_019113
19q13.1-qter
Human
Human
MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
< 0.1 ng/µg of protein (< 1EU/µg)
> 90% by SDS-PAGE & HPLC analyses
FGF-21, in the absence of betaKlotho, shows weak activity of thymidine uptake by BaF3 cells expressing FGF receptors.
182
Lyophilized
19.5 kDa
E. coli
Beschrijving
FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal gro
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