FGB-antilichaam

The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

2244

P02675

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 202-491 of human FGB (NP_005132.2) .

Unconjugated

Primary Antibodies

Other

Affinity purification

Mouse heart

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 56kDa

IgG

FGB

Mouse liver

Fibrinogen beta chain

Homo sapiens

FGB, fibrinogen beta chain, fibrinogen, B beta polypeptide

WB, IHC

Liquid