FGD1 Antilichaam

This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.

2245

P98174

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FGD1 (NP_004454.2) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 110kDa

IgG

FGD1

BxPC-3

HepG2

U2OS

FYVE, RhoGEF and PH domain containing 1

Homo sapiens

FGD1, AAS, FGDY, MRXS16, ZFYVE3

WB, IHC, IF

Liquid