FGF2 Mouse Monoclonal Antibody [Kloon ID: LBI3D9]

BFGF is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Carrier-free (BSA/glycerol-free) BFGF mouse monoclonal antibody, clone LBI3D9

BFGF; FGF-2; FGFB; HBGF-2

Homo sapiens fibroblast growth factor 2 (FGF2), transcript variant 1, mRNA.

2247

P09038

Unconjugated

MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

WB 1:1000, IHC 1:50, IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Secreted Protein

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

FGF2

https://www.ncbi.nlm.nih.gov/gene/?term=2247

https://www.uniprot.org/uniprot/P09038