FH Mouse Monoclonal Antibody [Kloon ID: LBI1F10]

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) FH mouse monoclonal antibody, clone LBI1F10

FMRD; HLRCC; LRCC; MCL; MCUL1

Homo sapiens fumarate hydratase (FH), mRNA; nuclear gene for mitochondrial product.

2271

P07954

Unconjugated

Citrate cycle (TCA cycle), Metabolic pathways, Pathways in cancer, Renal cell carcinoma

Citrate cycle (TCA cycle), Metabolic pathways, Pathways in cancer, Renal cell carcinoma

WB 1:1000, IHC 1:50, IF 1:100, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

FH

https://www.ncbi.nlm.nih.gov/gene/?term=2271

https://www.uniprot.org/uniprot/P07954