Fibrilline-antilichaam [10C1.3]

The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear. There is an aberrant expression of fibrillin in Marfan syndrome. The epitope for the monoclonal antibody 11C1.3 has been found to be within exons 18-20 (a.a. 723-909) .

2200

Q75N89

Q75N89

Human, Bovine, Japanese Macaque

Microfibrils from the zonular apparatus of bovine eye

[11C1.3]

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

0.2 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG1

Fibrillin

Fibrillin Antibody [11C1.3] for use in immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, and immunoprecipitation assays.

FBN1

Fibrillin 1

Homo sapiens

FBN1

Flow

Liquid