Filamine

2316

Chicken, Guinea Pig, Human, Mouse, Rabbit, Rat

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Recognizes native, full-length human filamin (actin-binding protein) at 270-280kD and the 190kD N-terminal calpain cleavage fragment of filamin. Following induction of apoptosis in U937 cells, the antibody recognizes 170, 150, and 120kD N-terminal cleavage fragments of the full-length form presumably resulting from cleavage by activated caspase-3. Species Crossreactivity: chicken, guniea pig, mouse, rabbit and rat

[FLNA; FLNA; FLN; FMD; MNS; OPD; ABPX; CSBS; CVD1; FLN1; NHBP; OPD1; OPD2; XLVD; XMVD; FLN-A; ABP-280; FLN; FLN1; FLN-A; ABP-280]

[Filamin]

[filamin-A isoform 2; Filamin-A; filamin-A; filamin-1; alpha-filamin; non-muscle filamin; actin binding protein 280; endothelial actin-binding protein; filamin A, alpha; Actin-binding protein 280; ABP-280; Alpha-filamin; Endothelial actin-binding protein; Filamin-1; Non-muscle filamin]

160420317

NP_001104026.1

NM_001110556.1

P21333