FIT-039 (standaard)

FIT-039 (Standard) is the analytical standard of FIT-039. This product is intended for research and analytical applications. FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.

1113044-49-7

12352100

CDK; CMV; DNA/RNA Synthesis; HSV; Reference Standards

Anti-infection; Cell Cycle/DNA Damage; Others

Infection

FC1=CC(NC(C2=CC=NC=C2)=S)=C(N3CCCCC3)C=C1

C17H18FN3S

315.41

[1]Makoto Yamamoto, et al. CDK9 Inhibitor FIT-039 Prevents Replication of Multiple DNA Viruses. J Clin Invest. 2014 Aug;124 (8) :3479-88.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-18944R/

Reference Standards