FK 584

FK 584 is a potent detrusor muscle contraction inhibitor. FK 584 possesses potent antimuscarinic activity and weak calcium channel blocking activity. FK 584 has demonstrated potent detrusor muscle inhibitory activity in various experimental models with a manageable risk of mydriasis. FK 584 can be used to study overactive bladder (OAB) .

138951-54-9

12352005

H302-H315-H319-H335

Calcium Channel; mAChR

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Metabolic Disease; Neurological Disease

CC(C)(C)N[C@H]1CC(C2=CC=CC=C2)(C3=CC=CC=C3)C=C1

C21H25N

291.43

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

[1]Taniguchi K, et al. Agents for the treatment of overactive detrusor. VIII. Synthesis and pharmacological properties of 4,4-diphenyl-2-cycloalkenylamines including FK584 and 3,3- or 4,4-diphenylcycloalkylamines. Chem Pharm Bull (Tokyo) . 1995 Jan;43 (1) :71-7.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-19228/

Reference compound2

Phase 2