
FK-664
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
FK-664 is a leukotriene inhibitor. FK-664 enhances ventricular contractility and shortens the time to peak tension in cardiac cells. FK-664 reduces mean circulating pressure (MCP) in a canine model of heart failure. FK-664 can be used in research on cardiovascular diseases such as heart failure[1][2].
94936-90-0
12352005
Leukotriene Receptor
GPCR/G Protein
Cardiovascular Disease
O=C1N(C)/C(C=C(N1CC)C2=CC(OC)=C(OC)C=C2)=N/C3=C(C)C=C(C)C=C3C
C24H29N3O3
407.51
[1]Kodama I, et al. Electrophysiological effects of FK664, a new cardiotonic agent, on preparations from guinea pig ventricle and from rabbit sino-atrial node. Cardiovasc Res. 1989 May;23 (5) :369-77.|[2]Sudo Y, et al. The effect of FK664, a new cardiovascular drug, on systemic capacitance vessels in anesthetized dogs. Life Sci. 1992;51 (25) :PL261-5.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19020/
Reference compound1
Phase 2
Beschrijving
FK-664 is a leukotriene inhibitor. FK-664 enhances ventricular contractility and shortens the time to peak tension in cardiac cells. FK-664 reduces mean circula
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