FKBP12 (FKBP1A) Mouse Monoclonal Antibody [Kloon ID: LBI3B3]

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) FKBP1A mouse monoclonal antibody, clone LBI3B3

FKBP-1A; FKBP-12; FKBP1; FKBP12; PKC12; PKCI2; PPIASE

Homo sapiens FKBP prolyl isomerase 1A (FKBP1A), transcript variant 1, mRNA.

2280

P62942

Unconjugated

WB: 1:200 - 1:1000, IHC 1:150, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

FKBP1A

https://www.ncbi.nlm.nih.gov/gene/?term=2280

https://www.uniprot.org/uniprot/P62942