FKBP3 Antilichaam - C-terminaal gebied : HRP (ARP54612_P050-HRP)

FK506 binding protein 3, 25kDa

FKBP-3, FKBP25, PPIase, FKBP-25

2287

Q00688

NP_002004

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human FKBP3

FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

UBC; EDC4; IGF2BP3; SYNCRIP; SEC16A; EIF2B2; EIF2B3; DYNLL1; RFC4; YBX1; NMT1; KRT18; ILF2; HNRNPU; HNRNPA2B1; DDX1; ABCF1; MAP1S; C14orf166; DIMT1; NELFB; SRPK1; FBXO25; BARD1; MYH10; PACSIN3; LRRFIP1; TIMELESS; Nedd4; NEDD4L; CALM1; HDAC2; HDAC1; YY1; C

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

FKBP3 is supported by BioGPS gene expression data to be expressed in 721_B, HeLa, Jurkat, MCF7

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

25kDa

Meng, X., Biochem. Genet. 40 (9-10), 303-310 (2002)

Wet Ice

224

FKBP3

FKBP3

Rabbit

Peptidyl-prolyl cis-trans isomerase FKBP3

NM_002013

EALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID