
Flonoltinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2387765-27-5
JAK2/FLT3-IN-1
JAK
Angiogenesis
C25H34FN7O
Flonoltinib (JAK2/FLT3-IN-1) is a potent and selective dual inhibitor of JAK2 and FLT3, with IC50 of of 0.8, 1.4, and 15 nM against JAK2, JAK2V617F, and FLT3, respectively, in in vitro kinase assays. It also inhibits cell proliferation and induces G2/M cell cycle arrest and apoptosis in Hemophagocytic Lymphohistiocytosis (HLH) patients' CD8+T cells, CTLL2 cells, and RAW 264.7 cells.
Beschrijving
Flonoltinib Beschikbaar in 25 mg. Bestel eenvoudig online met snelle levering.
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