FLT1 Antilichaam - C-terminal regio : HRP (ARP61021 P050-HRP)

Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)

FLT, FLT-1, VEGFR1, VEGFR-1

2321

P17948-6

Human, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the C-terminal region of Human FLT1

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig) -like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

SRPK1; VEGFA; Nedd4; UBC; ATR; NRP2; NRP1; VEGFB; PTK2B; PGF; PTK2; SHC1; NCK1; PLCG2; KDR; PTPN11; PLCG1; FLT1; YES1; CRK; FYN; CTNNB1; GRB2; SHC2; PIK3R1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

There is BioGPS gene expression data showing that FLT1 is expressed in HepG2

0.5 mg/ml

Cow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 77%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

50kDa

Wet Ice

463

FLT1

FLT1

Rabbit

Vascular endothelial growth factor receptor 1

DLRVTSKSKESGLSDVSRPSFCHSSCGHVSEGKRRFTYDHAELERKIACC