Fludarabine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A synthetic adenosine analog that inhibits DNA biosynthesis and is a clinically useful antineoplastic agent.1 In cells fludarabine accumulates as its 5’-triphosphate (F-ara-ATP) for which the rate-limiting step in formation is the conversion of fludarabine to its monophosphate.2 F-ara-ATP has multiple mechanisms of action including inhibition of ribonucleotide reductase, DNA polymerase, ligase and primase.2 A frequently used agent in myeloablative conditioning regimens for allogeneic hematopoietic cell transplantation.3 Immunosuppressive effects are mediated via inhibition of TNF-stimulated production of IL-2 and IFN- through inactivation of NFB.4 Antagonist at adenosine A1 receptors.5
Unconjugated
White solid
-20°C
Beschrijving
Fludarabine Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
CYP707A2 Antibody
GTR17947107
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100 Tests
Eco Alu MTP (HxD) 6x7=42 plates 35mm, 223x630x135mm
TE15336
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Arachis hypogaea Lectin (PNA) - Biotinylated
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Oxidative Stress Combo Assay Tissue Kit
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Benzonase ELISA Kit
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Recent gezochte producten
Recombinant Deinococcus radiodurans Protein RecA (recA)
MBS1071366-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Protein ApaG (apaG)
MBS1302345-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Protein grpE (grpE)
MBS1306645-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans GTPase obg (obg)
MBS1312662-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans GTPase Era (era)
MBS1418228-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans GTPase Der (der)
MBS1445159-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Enolase (eno)
MBS1455279-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Protein nrdI (nrdI)
MBS1483359-01
0.05 mg (E-Coli)