FluoSiteTM Anti-FOLR1 Antilichaam, FITC-Labeled

Folate receptor alpha (FOLR1) is a glycosylphosphatidylinositol (GPI) -anchored membrane protein that transports folate (vitamin B9) into cells. FOLR1 is overexpressed in multiple cancers such as cervical cancer, ovarian cancer, breast cancer, and brain carcinomas, and FOLR1 overexpression is associated with poor patient prognosis and increased cancer progression. The overexpression of FOLR1 in a variety of cancerous tissues makes it a valuable target for drug development. There are currently multiple drugs in clinical trials that target FOLR1.

This anti-FOLR1 (Folate receptor alpha) antibody is a purified monospecific recombinant antibody, which is labeled with fluorescein isothiocyanate (FITC) . This antibody has been tested by flow cytometry for specific binding to human FOLR1 on the surface of FOLR1 CHO Cell Line (BPS Bioscience #78360) .FluoSite™is a tag-based method for site-specific conjugation of antibodies with fluorophores, ensuring the labeling site is far from the antigen-binding domain to preserve antibody functionality. This precise, consistent labeling ensures the homogeneity of the labeled antibody preparation, making it ideal for flow cytometry and other high-sensitivity applications.

P15328

This antibody recognizes human FOLR1. It has not been tested in other species.

Fluorescein isothiocyanate (FITC) is a derivative of fluorescein and has an excitation and emission spectrum peak wavelengths of approximately 495 nm and 519 nm, causing it to fluoresce green.

Useful for studying the expression of FOLR1 on the cell surface by flow cytometry.

Protein A affinity chromatography from HEK293 supernatant.

≥ 90%

Aqueous buffer solution.

+4°C (Gel Packs)

At least 6 months at +4°C. Protect from prolonged exposure to light. DO NOT FREEZE. The antibody solution should be stored undiluted between +2°C and +8°C.

8 mM Phosphate, pH 7.4,110 mM NaCl, 2.2 mM KCl, 0.09% Sodium Azide, 0.2% BSA, and up to 20% glycerol. May contain a protein stabilizer.