FMRP (FMR1) Mouse Monoclonal Antibody [Kloon ID: LBI3B4]

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1) . Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) FMR1 mouse monoclonal antibody, clone LBI3B4

FMRP; FRAXA; POF; POF1; POFX

Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO1, mRNA.

2332

Q06787

Unconjugated

WB 1:500, IHC 1:150, IF 1:100, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

FMR1

https://www.ncbi.nlm.nih.gov/gene/?term=2332

https://www.uniprot.org/uniprot/Q06787