FOG-001
Gecertificeerd

FOG-001

Catalog #: TP3124-01
Maat: 10 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

CAS Number

3044032-95-0

Target

Wnt/beta-catenin

Related Pathways

Cytoskeletal Signaling, Stem Cells

Bioactivity

FOG-001 is an efficient inhibitor of β-catenin, with an IC50 value lower than 50 nM. This compound can block the interaction between β-catenin and T-cell factor (TCF) transcription factors, thereby interfering with the related signaling pathways. FOG-001 can effectively inhibit cell proliferation and induce cell cycle arrest. In a mouse xenograft tumor model carrying COLO320DM colon cancer cells (with APC and TP53 mutations), FOG-001 exhibits significant anti-tumor activity. Therefore, FOG-001 is applicable to the research on the mechanism of colon cancer occurrence and treatment.

Molecular Formula

C102H134N18O25S2

Molecular Weight

2076.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Beschrijving

FOG-001 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamFOG-001
Categorie
Beschikbare grootte10 mg
CatalogusnummerTP3124-01