Foretinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
849217-64-7
GSK1363089, EXEL-2880, XL-880, GSK089
C07528-5mg
C-Met
Protein Tyrosine Kinase
COC1=CC2=C (C=CN=C2C=C1OCCCN3CCOCC3) OC4=C (C=C (C=C4) NC (=O) C5 (CC5) C (=O) NC6=CC=C (C=C6) F) F
C34H34F2N4O6
Foretinib is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met (c-Met) and KDR with IC50 of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit (c-Kit), PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.
2 years -80 in solvent
Beschrijving
Foretinib Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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