Forsyshiyanine A

Foryshiyanine A is a triterpenoid alkaloid. Foryshiyanine A possesses anti-inflammatory activity, inhibiting the release of β-glucuronidase from rat polymorphonuclear leukocytes. Foryshiyanine A exhibits antiviral activity, with an EC50 of 4.5 μM against respiratory syncytial virus (RSV) and an IC50 of 7.3 μM against influenza A virus (H1N1) . Foryshiyanine A reduces viral load by disrupting viral replication and entry. Foryshiyanine A may be used for the researches of inflammation and infection[1][2].

2767053-65-4

12352005

Influenza Virus; RSV; β-glucuronidase

Anti-infection; Metabolic Enzyme/Protease

COVID-19-anti-virus

Infection

[H][C@@]12CCC3=NC(C)=CC=C3[C@]1(CCC[C@@]2(CO)C)C

C17H25NO

259.39

[1]Zhao L, et al. Alkaloids bearing rare skeletons from Forsythia suspensa with anti-inflammatory and anti-viral activities in vitro. Phytochemistry. 2021;186:112739.|[2]Rfaish SY, et al. Semisynthesis of Forsyshiyanine A and a Derivative with Significant Anti-Pancreatic Cancer Activity. J Nat Prod. 2025;88 (11) :2781-2788.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N17236/

Natural Products

No Development Reported