Fosfatase en angiotensine-homo-adenovirus (Ad-PTEN)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
Phosphatase and tensin homolog Adenovirus
41106621
3822190000
Pre-Made
Dry Ice
-80C
12 Months
Ad-PTEN
Human Adenovirus Type5 (dE1/E3)
CMV (ubiquitous)
DMEM, 2% BSA, 2.5% Glycerol
1x10^10 PFU/ml
Beschrijving
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylin
Specificaties
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