Fosfo-alfa Adducine (Ser436) Polyklonale Antilichaam, FITC-vervoeging

Adducins are a family of cytoskeleton proteins encoded by three genes (Alpha, Beta, Gamma) . Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organization. Adducin Alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin Alpha and Adducin Gamma is ubiquitous in contrast to the restricted expression of Adducin Beta. Adducin Beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice.

Alpha Adducinphospho S436; alpha Adducinphospho Ser436; p-alpha AdducinS436; p-alpha AdducinSer436; ADD 1; ADD A; ADD1; ADD1 protein; ADDA; ADDA_HUMAN; Adducin 1 alpha; Adducin 1 alpha; Alpha adducin; Alpha-adducin; Erythrocyte adducin alpha subunit; Erythrocyte hosphor subunit alpha; Erythrocyte adducin subunit alpha.

118

Ser436

Cytoplasm, Cell membrane

Human, Mouse

Phospho-alpha Adducin (Ser436)

FITC

KLH conjugated synthetic phosphopeptide derived from human alpha Adducin around the phosphorylation site of Ser436

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

494nm/518nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

118

Rat, Dog, Cow, Horse, Chicken