Fosfo-APC6 (Thr560) Polyklonale Antilichaam, Cy7 Vervoeging

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Cell division cycle protein 16 homolog; Anaphase-promoting complex subunit 6; APC6; CDC16 homolog; CDC16Hs; Cyclosome subunit 6; CDC16; ANAPC6

8881

Ser560

Cytoplasm

Phospho-APC6 (Thr560)

Cy7

KLH conjugated synthetic phosphopeptide derived from human APC6 around the phosphorylation site of Ser560

IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

743nm/767nm

1µg/µl

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

8881

Human, Mouse, Rat, Dog, Cow, Sheep, Pig