Fosfo-BTK-Y223 Rabbit pAb (AMR00846N)

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-BTK-Y223 Rabbit pAb (AMR00846N) .

AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA; BTK

695

Q06187

Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein

WB (Mus musculus, Rattus norvegicus)

WB 1:500 - 1:2000 IF 1:20 - 1:100

Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Calculated MW: 76kDa/79kDa Observed MW: Refer to Figures

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=695

https://www.uniprot.org/uniprot/Q06187

ALYDY