Fosfo-CHEK1 (317) antilichaam
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
Serine/threonine-protein kinase Chk1|CHK1 checkpoint homolog|Cell cycle checkpoint kinase|Checkpoint kinase-1|CHEK1|CHK1
1111
O14757
• Rabbit
Human
Phospho-CHEK1-S317
Phospho-CHEK1 (S317)
• Polyclonal
• IgG
Immunogen affinity purified
WB: 1:500 - 1:2000
≥95% as determined by SDS-PAGE
Liquid
60 kDa
4°C with ice bag
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
ELISA, WB
Beschrijving
Fosfo-CHEK1 (317) antilichaam Beschikbaar in 100 µg. Bestel eenvoudig online met snelle levering.
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