Fosfo-EPB41 (Tyr418 + Tyr660) Polyklonale Antilichaam

The 4.1 gene family encodes a group of multifunctional cytoskeletal proteins (4.1R, 4.1G, 4.1N and 4.1B), which are predominantly expressed in the nervous system. 4.1G is a protein that stabilizes spectrin-actin interactions and is associated with hereditary elliptocytosis. Red blood cell 4.1, designated 4.1R, is a multifunctional protein that is essential for maintaining erythrocyte shape and membrane mechanical properties. Both 4.1R and 4.1G are distributed in a unique pattern in the cerebellum and are believed to modulate the membrane mechanical properties of neuronal cells by promoting fodrin/actin association. 4.1N and 4.1B, designated EPB41L1 and EPB41L3, respectively, are strongly expressed in the brain. to 4.1N have been reported to detect mulitple forms, each enriched in postsynaptic density preparations relative to brain homogenate. to 4.1B have been reported to detect two forms.

EPB41 phospho Y418 + Y660; EPB41 phospho Tyr418 + Tyr660; p-EPB41 Y418 + Y660; p-4p-EPB41 Tyr418 + Tyr660; 4.1R; 41_HUMAN; Band 4.1; E41P; EL 1; EL1; Elliptocytosis 1; Elliptocytosis 1 RH linked; EPB 4.1; EPB 41; EPB4.1; Epb41; Erythrocyte membrane protein band 4.1 elliptocytosis 1 RH linked; Erythrocyte membrane protein band 4.1; Erythrocyte surface protein band 4.1; HE; P4.1; Protein 4.1.

2035

Tyr418 + Tyr660

Cytoplasm, Nucleus

Phospho-EPB41 (Tyr418 + Tyr660)

Unconjugated

KLH conjugated synthetic phosphopeptide derived from human EPB41 around the phosphorylation site of Tyr418 + Tyr660

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

1µg/µl

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

2035

Human, Mouse, Rat, Cow, Sheep, Pig, Horse, Chicken