Fosfo-Erk1 (Thr202 + Tyr204) Polyklonale Antilichaam, PerCP-vervoeging

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

ERK/MAPKphospho T202/Y204; p44/42 MAP KinaseThr202; ERK 1; ERK; ERK-1; ERK1; Extracellular Signal Regulated Kinase 1; Extracellular signal related kinase 1; Extracellular signal-regulated kinase 1; HGNC6877; HS44KDAP; HUMKER1A; MAP kinase 1; MK03_RAT; MAP Kinase; MAP kinase isoform p44; MAPK 1; MAPK; MAPK1; MAPK3; MGC20180; Mitogen-activated protein kinase 1; OTTHUMP00000174538; OTTHUMP00000174541; p44 ERK1; p44 MAPK; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK

5595

Thr202/Tyr204

Cytoplasm

Human, Mouse, Rat

Phospho-Erk1 (Thr202 + Tyr204)

PerCP

KLH conjugated synthetic phosphopeptide derived from human ERK1 around the phosphorylation site of Thr201/204

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

482nm/677nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

5595

Dog, Cow, Horse, Chicken, Rabbit, GuineaPig