Fosfo-Estrogeen Receptor alfa (Ser106) Polyklonale Antilichaam, AbBy FluorTM 405 Vervoeging

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]

Estrogen Receptor alpha (phospho S106) ; p-Estrogen Receptor alpha (phospho S106) ; DKFZp686N23123; ER alpha; ER; ER-alpha; Era; ESR; ESR1; ESR1_HUMAN; ESRA; Estradiol receptor; Estrogen nuclear receptor alpha; Estrogen receptor 1; Estrogen receptor alpha 3*,4,5,6,7*/822 isoform; Estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isoform; Estrogen receptor alpha delta 3*,4,5,6,7*/819 2 isoform; Estrogen receptor alpha delta 4 +49 isoform; Estrogen receptor alpha delta 4*,5,6,7*/654 isoform; Estrogen receptor alpha delta 4*,5,6,7,8*/901 isoform; Estrogen receptor; NR3A1; Nuclear receptor subfamily 3 group A member 1.

2099

P03372

Ser106

Cytoplasm, Nucleus, Cell membrane

Human, Rat

Phospho-Estrogen Receptor alpha (Ser106)

AbBy Fluor™ 405

KLH conjugated Synthesised phosphopeptide derived from human ER alpha around the phosphorylation site of Ser106

FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

401nm/421nm

1µg/µl

FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

2099

Mouse, Cow, Pig, Horse